Influenza A virus (IAV) is one of the major global public health concerns but the emerging resistance of IAV to
currently available antivirals requires the need to identify potential alternatives. Polyphenol rich sugarcane
extract (PRSE) is an extract prepared from the sugarcane plant Saccharum Officinarum. We showed that treatment of IAV-infected cells with PRSE results in a dose-dependent inhibition of virus infection at concentrations that were non-cytotoxic. PRSE treatment limited the early stages of infection, reducing viral genome replication, mRNA transcription and viral protein expression. In conclusion, we show that PRSE displays antiviral activity against a broad range of IAV strains, in vitro. Read More: sugarcane extract influenza
